EU Patient- cEntric clinicAl tRial pLatform

akronüüm: EU-PEARL
algus:
lõpp:
 
programm: H2020 - Horisont 2020
alaprogramm: HEALTH - Tervishoid, demograafilised muutused ja heaolu
instrument: JTI-IMI2-RIA
projektikonkurss: H2020-JTI-IMI2-2018-15-two-stage
projekti number: 853966
kestus kuudes: 42
partnerite arv: 36
 
lühikokkuvõte: EU-PEARL has the ambition of transforming the current approach of conducting single-compound clinical trials into the use of cross-company Integrated Research Platforms (IRPs), taking into consideration both patients’ interests and the opportunities from novel molecules for addressing medical needs. Patient-centric data and knowledge sharing have the potential to accelerate the development of new treatments and reduce the operational costs of clinical trials. EU-PEARL will improve clinical effectiveness, patients’ satisfaction and societal access to timely and affordable medicines and it will shape the clinical trials of the future. This will change the industry paradigm from competition to cooperation in four disease areas and provide the framework for designing IRPs in other disease areas. The main objectives of EU-PEARL are: (1) To create a reusable, accessible and sustainable modular IRP for the design and execution of patient-centric, cross- company IRP in any disease area with unmet needs; (2) To set up the open, dynamic, patient inclusive IRP governance structure that will manage the appropriate regulatory, ethical, legal, statistical and data utilisation requirements of the IRP; (3) To disseminate and exploit the EU-PEARL paradigm through the provision of the necessary common tools, procedures, expertise and operational skills working to the highest scientific, regulatory and ethical standards and best practices, developed jointly by public and industry partners in a consensus-based approach; and (4) To create trial-ready IRP networks in the four disease areas of Major Depressive Disorder (MDD), Tuberculosis (TB), Non-Alcoholic Steatohepatitis (NASH) and Neurofibromatosis (NF).
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES Joan X Comella Carnice http://www.vhir.org
2 partner EATRIS ERIC NL www.eatris.eu
3 partner SYNAPSE RESEARCH MANAGEMENT PARTNERS SL ES www.synapse-managers.com
4 partner MEDIZINISCHE UNIVERSITAET WIEN AT www.meduniwien.ac.at
5 partner KATHOLIEKE UNIVERSITEIT LEUVEN BE www.kuleuven.be
6 partner KING'S COLLEGE LONDON UK www.kcl.ac.uk
7 partner UNIVERSITA VITA-SALUTE SAN RAFFAELE IT www.unisr.it
8 partner ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL www.erasmusmc.nl
9 partner LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE www.uni-muenchen.de
10 partner CHARITE - UNIVERSITAETSMEDIZIN BERLIN DE www.charite.de
11 partner ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS FR www.aphp.fr
12 partner CUSTODIX NV BE www.custodix.com
13 partner THE EUROPEAN INSTITUTE FOR INNOVATION THROUGH HEALTH DATA BE www.i-hd.eu
14 partner BERRY CONSULTANTS LLP UK www.berryconsultants.com
15 partner ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK FR www.ecrin.org
16 partner FORUM EUROPEEN DES PATIENTS (FPE) LU www.eu-patient.eu
17 partner UNIVERSITY OF NEWCASTLE UPON TYNE UK www.newcastle.ac.uk
18 partner EUROSCAN INTERNATIONAL NETWORK EV DE www.euroscan.org
19 partner BUNDESINSTITUT FUR IMPFSTOFFE UND BIOMEDIZINISCHE ARZNEIMITTEL DE www.pei.de
20 partner THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK www.ox.ac.uk
21 partner UNIVERSITA DEGLI STUDI DI MILANO IT www.unimi.it
22 partner DOCUMENTAL OU EE www.documental.ee
23 partner THE UNIVERSITY OF MANCHESTER UK www.manchester.ac.uk
24 partner JANSSEN PHARMACEUTICA NV BE http://www.janssen.com/
25 partner NOVARTIS PHARMA AG CH
26 partner ALLERGAN LIMITED UK www.allergan.co.uk
27 partner ASTRAZENECA AB SE www.astrazeneca.com
28 partner NOVO NORDISK A/S DK www.novonordisk.com
29 partner OTSUKA NOVEL PRODUCTS GMBH DE
30 partner PFIZER LIMITED UK www.pfizer.com
31 partner SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT FR sanofi-aventis.com
32 partner INSTITUT DE RECHERCHES INTERNATIONALES SERVIER FR http://www.servier.fr
33 partner TEVA PHARMACEUTICAL INDUSTRIES LIMITED IL http://www.tevapharm.com/
34 partner CHILDREN'S TUMOR FOUNDATION US https://www.ctf.org/
35 partner Springworks Therapeutics US www.springworkstx.com
36 partner GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT NON PROFIT ORGANISATION US http://www.tballiance.org/home/home.php