Innovative Nanoinformatics models and tools: towards a Solid, verified and Integrated Approach to Predictive (eco)Toxicology (NanoSolveIT)

akronüüm: NanoSolveIT
algus: 2019-01-01
lõpp: 2023-02-28
 
programm: H2020 - Horisont 2020
alaprogramm: LEIT - Juhtkoht tööstustehnoloogias
instrument: RIA
projektikonkurss: H2020-NMBP-TO-IND-2018
projekti number: 814572
kestus kuudes: 50
partnerite arv: 25
 
lühikokkuvõte: NanoSolveIT will introduce a ground-breaking in silico Integrated Approach to Testing and Assessment (IATA) for the environmental health and safety of Nanomaterials (NM), implemented as a decision support system packaged as a standalone open software and a Cloud platform. NanoSolveIT will develop and deliver: (i) a reliable user friendly knowledge-based infrastructure for data hosting, sharing and exploitation, (ii) NM fingerprints, sets of nanodescriptors and properties that can be predictively linked to NM functionality, exposure and hazard, thereby supporting NM grouping, safe-by-design (SbD) and regulatory risk assessment (RA), (iii) innovative methodologies for NMs predictive (eco)toxicology underpinned by artificial intelligence and state-of-the-art in silico techniques, and, (iv) integration with multi-scale modelling, RA and governance frameworks developed in EU H2020 funded and in the forthcoming NMBP-13 project(s). NanoSolveIT will deliver a validated, sustainable, multi-scale nanoinformatics IATA, tested and demonstrated at TLR6 via OECD style IATA case studies, serving the needs of diverse stakeholders at each stage of the NMs value chain, for assessment of potential adverse effects of NM on human health and the environment. NanoSolveIT is fully aligned to the objectives of the EU-US Nanoinformactics Roadmap, addressing all 13 of its short, medium and long term milestones, and supports the recommendations of the EMMC on standards for developing material modelling software and OECD best practice. The NanoSolveIT consortium (EU and international partners) is the only grouping capable of delivering the ambitious goals of the NMBP-14-2018 call, since they have collectively driven most of the current progress in nanoinformatics: 81% of the nanoinormatics papers cited in the EU-US nanoinformatics roadmap had NanoSolveIT authors. NanoSolveIT will integrate across the consortium-wide modelling approaches to provide the IATA platform for in silico NMs RA.
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator NOVAMECHANICS LIMITED CY Andreas AFANTITIS www.novamechanics.com
2 partner THE UNIVERSITY OF BIRMINGHAM UK www.bham.ac.uk
3 partner NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA EL www.ntua.gr
4 partner UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN IE www.ucd.ie
5 partner TAMPEREEN KORKEAKOULUSAATIO SR FI https://www.tuni.fi/en
6 partner MISVIK BIOLOGY OY FI www.misvik.com
7 partner UNIVERSITEIT MAASTRICHT NL http://www.maastrichtuniversity.nl
8 partner QSAR LAB SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA PL
9 partner STOCKHOLMS UNIVERSITET SE www.su.se
10 partner DET NATIONALE FORSKNINGSCENTER FORARBEJDSMILJO DK www.nrcwe.dk
11 partner GEORG-AUGUST-UNIVERSITAT GOTTINGENSTIFTUNG OFFENTLICHEN RECHTS DE http://www.uni-goettingen.de
12 partner UNITED KINGDOM RESEARCH AND INNOVATION UK https://www.ukri.org/
13 partner BIOMAX INFORMATICS AG DE www.biomax.com
14 partner Tartu Ülikool EE http://www.ut.ee
15 partner NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE NO www.nilu.no
16 partner BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG DE www.bam.de
17 partner THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL US www.unc.edu
18 partner THE REGENTS OF THE UNIVERSITY OF CALIFORNIA US http://www.universityofcalifornia.edu/
19 partner BOARD OF TRUSTEES OF JACKSON STATE UNIVERSITY US http://www.jsums.edu/
20 partner DUKE UNIVERSITY US www.duke.edu
21 partner LA TROBE UNIVERSITY AU www.latrobe.edu.au
22 partner NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES JP www.nies.go.jp
23 partner INDUSTRY-UNIVERSITY COOPERATION FOUNDATION OF HANYANG UNIVERSITY KR www.hanyang.ac.kr
24 partner NATIONAL HEALTH LABORATORY SERVICES ZA