Novel 1D photonic metal oxide nanostructures for early stage cancer detection

akronüüm: CanBioSe
algus: 2018-01-01
lõpp: 2021-12-31
 
programm: H2020 - Horisont 2020
alaprogramm: MSCA - Marie Skłodowska-Curie meetmed
instrument: MSCA-RISE - Teadus- ja innovatsioonitöötajate vahetus
projektikonkurss: H2020-MSCA-RISE-2017
projekti number: 778157
kestus kuudes: 48
partnerite arv: 9
 
lühikokkuvõte: The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic system in order to minimize dimensions and simplify the use of the detection system. The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization, bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs via new scientific papers and conference theses and strengthen a development of EU research human resources. Long lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator LATVIJAS UNIVERSITATE LV Donats ERTS http://www.lu.lv
2 partner VILNIAUS UNIVERSITETAS LT http://www.vu.lt
3 partner ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER FR www.enscm.fr
4 partner UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU PL www.amu.edu.pl
5 partner FONDAZIONE BRUNO KESSLER IT www.fbk.eu
6 partner EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ EE www.matecc.eu
7 partner BIOSENSOR S.R.L. IT www.biosensor.it
8 partner NANOPHARMA AS CZ www.nanopharma.cz