Infradev - European Paediatric Translational Research Infrastructure

akronüüm: ID-EPTRI
algus: 2018-01-01
lõpp: 2019-12-31
 
programm: H2020 - Horisont 2020
alaprogramm: INFRA - Euroopa Teadustaristud, sh e-Taristud
instrument: RIA
projektikonkurss: H2020-INFRADEV-2017-1
projekti number: 777554
kestus kuudes: 24
partnerite arv: 28
 
lühikokkuvõte: The general objective of this project is to design the framework for the European Paediatric Translational Research Infrastructure (EPTRI), a new Research Infrastructure (RI) aimed to enhance technology-driven paediatric research in discovery and early development phases to be translated into clinical research and paediatric use of medicines. The starting point of the proposal is the serious lack of medicines for children in EU and worldwide as well as the lack of a development model for paediatric medicines that integrates technology-driven aspects with clinical trials. The design for this new RI will be based on the following main pillars: - to harness efficiency and delivery of paediatric research activities and services strengthening collaboration within the scientific paediatric community; - to be a complementary RI in the context of the existing RIs covering the current gaps, while avoiding any duplication; - to contribute to a one-stop-shop for advice in paediatric drug development; - to develop a paediatric research infrastructure facility collaborating with already established Research Infrastructures and Common Services. To prepare a valuable Conceptual Design Report (CDR), the project encompasses three phases. During the Context Analysis phase, that will be performed in 5 technical and scientific domains (1-Paediatric Medicines Discovery and Preclinical Studies, 2-Biomarkers, 3-Paediatric Pharmacology, 4-Formulation Science, 5-Underpinning Paediatric Studies) the perceived value and the possible gaps to be covered will be estimated by enquiring the scientific Communities, the concerned national Authorities and many other Stakeholders. During the Operational phase, the different components of the new RI will be organised including governance model strategies for interaction with national Authorities and the existing RIs, the IT-architecture model, services to be provided and a business plan. In the second year, a Feasibility phase is proposed to develop virtual exercises simulating the operations of the RI. The final result of the project will be the CDR to realize EPTRI.
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator CONSORZIO PER VALUTAZIONI BIOLOGICHE E FARMACOLOGICHE IT Donato BONIFAZI www.cvbf.net
2 partner FONDAZIONE PENTA-FOR THE TREATMENT AND CARE OF CHILDREN WITH HIV-ONLUS IT www.penta-id.org
3 partner EATRIS ERIC NL www.eatris.eu
4 partner UNIVERSITY COLLEGE LONDON UK http://www.ucl.ac.uk
5 partner ATHINA-EREVNITIKO KENTRO KAINOTOMIAS STIS TECHNOLOGIES TIS PLIROFORIAS, TON EPIKOINONION KAI TIS GNOSIS EL www.athena-innovation.gr
6 partner BIOBANKS AND BIOMOLECULAR RESOURCESRESEARCH INFRASTRUCTURE CONSORTIUM(BBMRI-ERIC) AT www.bbmri-eric.eu
7 partner THE CYPRUS FOUNDATION FOR MUSCULAR DYSTROPHY RESEARCH CY www.cing.ac.cy
8 partner ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS FR www.aphp.fr
9 partner STICHTING KATHOLIEKE UNIVERSITEIT NL www.ru.nl
10 partner THE UNIVERSITY OF LIVERPOOL UK www.liverpool.ac.uk
11 partner ROMANIAN ANGEL APPEAL RO www.raa.ro
12 partner INSTYTUT POMNIK CENTRUM ZDROWIA DZIECKA PL www.czd.pl
13 partner OSPEDALE PEDIATRICO BAMBINO GESU IT www.ospedalebambinogesu.it
14 partner FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI) CZ http://www.biomed.cas.cz/fgu/en/index.php
15 partner FUNDACIO SANT JOAN DE DEU ES www.fsjd.org
16 partner NIZHEGORODSKIY GOSUDARSTVENNIY UNIVERSITET IM N.I. LOBACHEVSKOGO RU http://www.unn.ru/eng
17 partner SERVICIO MADRILENO DE SALUD ES http://cort.as/10Yf
18 partner ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK FR www.ecrin.org
19 partner QENDRES SPITALORE UNIVERSITARE NENETEREZA TIRANE AL
20 partner TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL www.technion.ac.il
21 partner Tartu Ülikool EE www.ut.ee
22 partner UNIVERSITATSKLINIKUM ERLANGEN DE www.uk-erlangen.de
23 partner SWISS CLINICAL TRIAL ORGANISATION CH www.scto.ch
24 partner VASTRA GOTALANDS LANS LANDSTING SE
25 partner UNIVERSITAIR MEDISCH CENTRUM UTRECHT NL www.umcutrecht.nl