Binding-activated fluorescent DNA/peptide chimeric probes for cancer imaging

akronüüm: CHIMERA
algus: 2013-11-01
lõpp: 2016-10-31
 
programm: FP7 - Euroopa Liidu 7. raamprogramm
alaprogramm: PEOPLE - Marie Curie tegevused
instrument: MC-IRSES - Marie Curie tegevused
projektikonkurss: FP7-PEOPLE-2013-IRSES
projekti number: 609850
kestus kuudes: 36
partnerite arv: 4
 
lühikokkuvõte: The overriding goal of this project is to mimic Nature in the design of novel nucleic acid/peptide chimera based nanodevices that can enable cancer imaging. We will design, engineer and optimize highly specific biomolecular nanodevices that undergo binding-induced conformational changes upon target binding and, in doing so, signal the presence of the cancer marker. This scientific goal of great relevance for the clinical implications will be achieved bringing together an international and interdisciplinary group of research teams and building a collaborative environment for research, innovation and technology transfer. This program will allow the exchange of knowledge and expertise through visiting training periods for participating early-stage and experienced researchers. The training will involve each single aspect of probe development and cancer imaging. The research teams involved in this project encompass the requisite expertise and each of them has a particular focus on a single step of optical probe development and testing on cancer cells. This program will help the integration and collaboration among the research teams and the establishment of a long-term collaboration between Europe and key Third Countries.
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA IT francesco Ricci http://www.uniroma2.it
2 partner Tartu Ülikool EE Tambet Teesalu http://www.ut.ee
3 partner UNIVERSITE DE MONTREAL CA Alexis Vallée-Bélisle http://www.umontreal.ca
4 partner SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Kazuki Sugahara http://www.sanfordburnham.org