Development of methods for genome-wide association studies

akronüüm: StatGnOfGenomeWideAS
algus: 2009-09-01
lõpp: 2011-08-31
 
programm: FP7 - Euroopa Liidu 7. raamprogramm
alaprogramm: PEOPLE - Marie Curie tegevused
instrument: MC-IEF
projektikonkurss: FP7-PEOPLE-IEF-2008
projekti number: 237423
kestus kuudes: 24
partnerite arv: 1
 
lühikokkuvõte: Genome-wide association studies have been very successful - and yet much of the genetic contribution to complex diseases remains unexplained. In-depth mining of GWA data sets may provide evidence of further novel variants: this could be through looking at epistasis, gene-environment interaction, disease sub-phenotypes, rare variants. These analyses can be applied to a range of data sets available to us including type 2 diabetes, Crohn's disease and anthropological traits including BMI, height and adiposity.
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1 koordinaator Tartu Ülikool EE Reedik Mägi http://www.ut.ee