Gaining Productivity, Cost Efficiency and Sustainability in the Downstreaming Processing of Bio Products by novel Integration and Intensification strategies

akronüüm: INTENSO
algus: 2012-08-01
lõpp: 2017-01-31
 
programm: FP7 - Euroopa Liidu 7. raamprogramm
alaprogramm: KBBE - Toit, põllumajandus ja biotehnoloogia
instrument: CP-TP - Koostööprojektid spetsiaalsetele gruppidele
projektikonkurss: FP7-KBBE-2012-6-singlestage
projekti number: 312004
kestus kuudes: 54
partnerite arv: 16
 
lühikokkuvõte: The European Life science and chemical industries increasingly depend on effi-cient, sustainable, and cost-effective bioprocessing platforms to remain competi-tive. A critical assessment of current bottlenecks during (bio) manufacturing clearly indicates that the recovery and purification of biologicals in large scale in responsible for many inefficiencies. INTENSO proposes an evaluation of the current situation of the downstream processing scenario with the aim of identifying inefficiencies and concomitantly introduce a debottlenecking overarching strategy. The later will be build up on the basis of a multidisciplinary approach, which considers opportunities to im-prove the process technology and underlying chemistry / biology and materials science at the same time. INTENSO will work alongside 4 technological axes, targeting promising and up-coming technologies and tailoring such technologies to the manufacturing of various classes of (bio) products. Intensification of individual unit operations and global process integration, as well as, dovetailing with fermentation / cell cultivation will be employed to the mentioned end. INTENSO will target new classes of (bio) products like Monoclonal Antibodies (Mabs), pDNA (e.g. for genetic vaccination), Virus Like Particles (VLP) or nano-plexes. All the mentioned new products are part of most industrial R&D pipelines and offer an excellent opportunity to introduce innovative bioprocessing. The results of the project are expected to contribute to the understanding of current industrial downstream processing practice, to the definition and alleviation of current inefficiencies, to the development and / or implementation of novel technologies, and to more efficient / sustainable and cost effective (bio) manufacturing. Various technologies will be studied utilizing a nano-to-process strategy so as to introduce integration / intensification during bioprocessing.
partneri jrk nr ja roll partneri nimi riik kontaktisik koduleht
1 koordinaator JACOBS UNIVERSITY BREMEN GGMBH DE Ronald Kieschnick http://www.jacobs-university.de/
2 partner BIA SEPARATIONS DOO SI Nika Lendero Krajnc http://www.biaseparations.com/
3 partner UNIVERSIDAD NACIONAL DE QUILMES AR Mariano Grasselli http://www.unq.edu.ar
4 partner CHIPRO GMBH DE Sebastian Thiem http://www.chipro.de
5 partner UNIVERSITAET FUER BODENKULTUR WIEN AT Alois Jungbauer http://www.boku.ac.at
6 partner ICOSAGEN AS EE Mart Ustav http://www.icosagen.com
7 partner SOFIISKI UNIVERSITET SVETI KLIMENT OHRIDSKI BG Valentina Ganeva http://www.uni-sofia.bg
8 partner PROXCYS NL Marcel Raedts http://www.proxcys.com
9 partner INSTITUTO SUPERIOR TECNICO PT Raquel Aires-Barros http://www.ist.utl.pt
10 partner INFOCONSULT GESELLSCHAFT FUR INFORMATIONSTECHNIK MBH DE Peter Knackfuß http://www.infoconsult.net
11 partner BIOMEDAL SL ES Cebolla Ramirez Angel http://www.biomedal.com
12 partner VIRTUALPIE LTD UK Mike Butcher http://www.bhrgroup.com
13 partner ERA BIOTECH ES Blanca Llompart http://www.erabiotech.com
14 partner GENERI BIOTECH CZ Martin Martin http://www.generi-biotech.com
15 partner ETHRIS GMBH DE Carsten Rudolph http://www.ethris.com
16 partner DSM BIOLOGICS COMPANY BV NL Rolf Douwenga http://www.dsm.com